Advances in stroke: genetics 2012.

Genetics of ischaemic stroke.

Recent advances in genomics and statistical computation have allowed us to begin addressing the genetic basis of stroke at a molecular level. These advances are at the cusp of making important changes to clinical practice of some monogenic forms of stroke and, in the future, are likely to revolutionise the care provided to these patients. In this review we summarise the state of knowledge in is...

Stroke genetics: prospects for personalized medicine

Epidemiologic evidence supports a genetic predisposition to stroke. Recent advances, primarily using the genome-wide association study approach, are transforming what we know about the genetics of multifactorial stroke, and are identifying novel stroke genes. The current findings are consistent with different stroke subtypes having different genetic architecture. These discoveries may identify ...

Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement From the American Heart Association.

Advances in genomics are enhancing our understanding of the genetic basis of cardiovascular diseases, both congenital and acquired, and stroke. These advances include finding genes that cause or increase the risk for childhood and adult-onset diseases, finding genes that influence how patients respond to medications, and the development of genetics-guided therapies for diseases. However, the ab...

Advances in Genetics, Proteomics, and Metabolomics Genetics of Atherothrombotic and Lacunar Stroke

Stroke genetics update.

The genetics of cerebrovascular disease is an area of increasing interest and advances. During the past year there have been a number of significant discoveries in the area that have increased our knowledge and understanding of the importance of genetics factors in the epidemiology of, etiology of, pathophysiology of, and recovery from cerebrovascular disease. This review will highlight some of...